ABSTRACT
Basal cell carcinoma (BCC) is the most common human malignant neoplasm, accounting for 75% of all non-melanoma skin cancer. The incidence of BCC is strongly correlated with sun exposure as well as older age. Therefore, the vast majority of BCCs is observed in elderly patients on the sun-exposed skin of the head and neck with a frequency of more than 80%. BCC is very rare on sun-protected skin such as the perianal and genital regions and other etiologic factors must be considered in these cases. Although the pathogenesis of vulvar BCC is unclear, early diagnosis is very important. Because BCC in these areas sometimes seems innocuous, it is recommended that a biopsy of all suspect lesions be performed. We report a woman with BCC of the vulva treated with wide local resection and reviews the literatures on this subject.
Subject(s)
Aged , Female , Humans , Accounting , Biopsy , Carcinoma, Basal Cell , Early Diagnosis , Head , Incidence , Neck , Skin , Skin Neoplasms , Solar System , VulvaABSTRACT
Subject(s)
Animals , Dogs , Artifacts , Bicuspid , Blood Platelets , Intercellular Signaling Peptides and Proteins , Mandible , Molar , Nitrogen Mustard Compounds , Osseointegration , Osteogenesis , Proto-Oncogene Proteins c-sis , Titanium , TransplantsABSTRACT
Clear cell adenocarcinoma (CCAC) is a rare cancer that comprises less than 9% of the cervical adenocarcinoma cases. We experienced a case of fertility-sparing radical abdominal trachelectomy for cervical clear cell adenocarcinoma (CCAC). Thus, reported it. A 27 year old female was diagnosed with clinical stage Ib cervical CCAC. She had no history of maternal exposure to diethylstilbestrol and had negative PAP cytology and HPV tests. She was treated with neoadjuvant chemotherapy followed by radical abdominal trachelectomy. After 2 cycles of postoperative adjuvant chemotherapy, the lesion disappeared completely in an imaging study, and potential fertility was preserved. Radical abdominal trachelectomy with chemotherapy may be a valuable approach for treating stage Ib cervical CCAC in women that wish to preserve potential fertility.
Subject(s)
Female , Humans , Adenocarcinoma , Adenocarcinoma, Clear Cell , Chemotherapy, Adjuvant , Diethylstilbestrol , Fertility , Maternal Exposure , Uterine Cervical NeoplasmsABSTRACT
Ameloblastomas are generally considered to be benign tumors of odontogenic epithelial origin with high local recurrence. Rarely ameloblastomas exhibit malignant behavior with development of metastases. In this report, we present a 19-year-old woman with ameloblastoma in the right ascending ramus and multiple recurrences. Eleven years after first therapy, ameloblastoma metastasized to ipsilateral submandibular lymph node. We also review literature about cause, treatment and work-up of malignant ameloblastoma.